Canagliflozin hemihydrate
Appearance: White to off white powder;
Specific rotation:+19 ° to+25 °;
Chloride: not exceeding 0.01%;
Sulfate: not exceeding 0.02%;
Regarding substances: individual impurities should not exceed 0.1%, and total impurities should not exceed 0.5%;
Moisture content: 1.6% to 2.7%;
Burning residue: not exceeding 0.1%;
Heavy metals: not exceeding 20 parts per million;
Content: 98.0%~102.0%.
Canagliflozin is a selective inhibitor of glucose cotransporter SGLT2 and an oral drug for the treatment of diabetes. It reduces blood sugar by decomposing glucose and expelling it from the body through the kidney. Canagliflozin is clinically used to treat type II diabetes.
Description
English name:Canagliflozin
Chemical name:(1S)-1,5-Anhydro-1-(3-{[5-(4-fluorophenyl)-2-thienyl]methyl}-4-methylphenyl)-D-glucitol hydrate (2:1);(2S,3R,4R,5S,6R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-6-(hydroxymethyl)oxane-3,4,5-triol,hydrate;D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, (1S)-, hydrate (2:1).
Molecular formula:C24H25FO5S
Molecular weight:453.52
CAS NO.:928672-86-0
LogP:5.87230
Additional information
| color | Red |
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